Metronidazole, popularly known as Flagyl is an antibiotic that is particularly effective at treating anaerobic infections (infections caused without the presence of air). It is one drug that readily comes to mind when diarrhoea comes calling. Although it may be taken with or without food, it should never be taken with alcohol. In fact, alcohol should be avoided while taking metronidazole and for three days after the course of metronidazole has finished.
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Interactions between alcohol (no matter how little) and metronidazole is very dangerous and can make a person very sick. Resulting symptoms include severe nausea and vomiting, flushing, fast heartbeat (tachycardia) and shortness of breath.
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It should be noted however that small amounts of alcohol can be found in hidden sources such as mouthwash, cold medicines and cough syrups. All these should be taken into consideration.